A Regulatory Feedback Loop between HIF-1α and PIM2 in HepG2 Cells

To survive under hypoxic conditions, cancer cells remodel glucose metabolism to support tumor progression. HIF transcription factor is essential for cellular response to hypoxia. The underlying mechanism how HIF is constitutively activated in cancer cells remains elusive. In the present study, we ch...

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Detalles Bibliográficos
Autores principales: Yu, Zhenhai, Zhao, Xiaoping, Ge, Yingying, Zhang, Teng, Huang, Liangqian, Zhou, Xiang, Xie, Lei, Liu, Jianjun, Huang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914973/
https://www.ncbi.nlm.nih.gov/pubmed/24505470
http://dx.doi.org/10.1371/journal.pone.0088301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914973/
https://www.ncbi.nlm.nih.gov/pubmed/24505470
http://dx.doi.org/10.1371/journal.pone.0088301

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