Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells

The androgen receptor (AR) stimulates and represses gene expression to promote the initiation and progression of prostate cancer. Here we report that androgen represses the miR-99a/let7c/125b-2 cluster through AR and anti-androgen drugs block the androgen-repression of the miRNA cluster. AR directly...

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Detalles Bibliográficos
Autores principales: Sun, Dandan, Layer, Ryan, Mueller, Adam C., Cichewicz, Magdalena A., Negishi, Masamitsu, Paschal, Bryce M., Dutta, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915043/
https://www.ncbi.nlm.nih.gov/pubmed/23503464
http://dx.doi.org/10.1038/onc.2013.77

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915043/
https://www.ncbi.nlm.nih.gov/pubmed/23503464
http://dx.doi.org/10.1038/onc.2013.77

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