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Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration

During DNA repair by homologous recombination (HR), DNA synthesis copies information from a template DNA molecule. Multiple DNA polymerases have been implicated in repair-specific DNA synthesis(1)–(3), but it has remained unclear whether a DNA helicase is involved in this reaction. A good candidate...

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Detalles Bibliográficos
Autores principales: Wilson, Marenda A., Kwon, YoungHo, Xu, Yuanyuan, Chung, Woo-Hyun, Chi, Peter, Niu, Hengyao, Mayle, Ryan, Chen, Xuefeng, Malkova, Anna, Sung, Patrick, Ira, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915060/
https://www.ncbi.nlm.nih.gov/pubmed/24025768
http://dx.doi.org/10.1038/nature12585