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Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration
During DNA repair by homologous recombination (HR), DNA synthesis copies information from a template DNA molecule. Multiple DNA polymerases have been implicated in repair-specific DNA synthesis(1)–(3), but it has remained unclear whether a DNA helicase is involved in this reaction. A good candidate...
Autores principales: | Wilson, Marenda A., Kwon, YoungHo, Xu, Yuanyuan, Chung, Woo-Hyun, Chi, Peter, Niu, Hengyao, Mayle, Ryan, Chen, Xuefeng, Malkova, Anna, Sung, Patrick, Ira, Grzegorz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915060/ https://www.ncbi.nlm.nih.gov/pubmed/24025768 http://dx.doi.org/10.1038/nature12585 |
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