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Osteoblasts stimulate the osteogenic and metastatic progression of castration-resistant prostate cancer in a novel model for in vitro and in vivo studies

Castration-resistant prostate cancer (CRPC) is strongly associated with sclerotic bone metastases and poor prognosis. Models that mimic human CRPC are needed to identify the mechanisms for prostate cancer (PC) growth in bone and to develop new therapeutic strategies. We characterize a new model, LNC...

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Detalles Bibliográficos
Autores principales: Hagberg Thulin, Malin, Jennbacken, Karin, Damber, Jan-Erik, Welén, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915083/
https://www.ncbi.nlm.nih.gov/pubmed/24292404
http://dx.doi.org/10.1007/s10585-013-9626-1