p53-dependent and p53-independent anticancer effects of different histone deacetylase inhibitors

BACKGROUND: Histone deacetylase inhibitors (HDACi) are promising antineoplastic agents, but their precise mechanisms of actions are not well understood. In particular, the relevance of p53 for HDACi-induced effects has not been fully elucidated. We investigated the anticancer effects of four structu...

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Detalles Bibliográficos
Autores principales: Sonnemann, J, Marx, C, Becker, S, Wittig, S, Palani, C D, Krämer, O H, Beck, J F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915118/
https://www.ncbi.nlm.nih.gov/pubmed/24281001
http://dx.doi.org/10.1038/bjc.2013.742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915118/
https://www.ncbi.nlm.nih.gov/pubmed/24281001
http://dx.doi.org/10.1038/bjc.2013.742

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