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Monitoring response to cytostatic cisplatin in a HER2(+) ovary cancer model by MRI and in vitro and in vivo MR spectroscopy

BACKGROUND: Limited knowledge is available on alterations induced by cytostatic drugs on magnetic resonance spectroscopy (MRS) and imaging (MRI) parameters of human cancers, in absence of apoptosis or cytotoxicity. We here investigated the effects of a cytostatic cisplatin (CDDP) treatment on (1)H M...

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Detalles Bibliográficos
Autores principales: Pisanu, M E, Ricci, A, Paris, L, Surrentino, E, Liliac, L, Bagnoli, M, Canevari, S, Mezzanzanica, D, Podo, F, Iorio, E, Canese, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915124/
https://www.ncbi.nlm.nih.gov/pubmed/24335926
http://dx.doi.org/10.1038/bjc.2013.758