TMPRSS4 regulates levels of integrin α5 in NSCLC through miR-205 activity to promote metastasis

BACKGROUND: TMPRSS4 is a membrane-anchored protease involved in cell migration and invasion in different cancer types including lung cancer. TMPRSS4 expression is increased in NSCLC and its inhibition through shRNA reduces lung metastasis. However, molecular mechanisms leading to the protumorigenic...

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Detalles Bibliográficos
Autores principales: Larzabal, L, de Aberasturi, A L, Redrado, M, Rueda, P, Rodriguez, M J, Bodegas, M E, Montuenga, L M, Calvo, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915125/
https://www.ncbi.nlm.nih.gov/pubmed/24434435
http://dx.doi.org/10.1038/bjc.2013.761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915125/
https://www.ncbi.nlm.nih.gov/pubmed/24434435
http://dx.doi.org/10.1038/bjc.2013.761

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