Ritonavir-Mediated Induction of Apoptosis in Pancreatic Cancer Occurs via the RB/E2F-1 and AKT Pathways

Recent observations suggest a lower incidence of malignancies in patients infected with HIV during treatment with Highly Active Anti-Retroviral Therapy (HAART) utilizing protease inhibitors. We investigated the effects of ritonavir, a FDA approved HIV protease inhibitor, on proliferation of pancreat...

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Detalles Bibliográficos
Autores principales: Batchu, Ramesh B., Gruzdyn, Oksana V., Bryant, Christopher S., Qazi, Aamer M., Kumar, Sanjeev, Chamala, Sreedhar, Kung, Shu T., Sanka, Ramana S., Puttagunta, Udaya S., Weaver, Donald W., Gruber, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915194/
https://www.ncbi.nlm.nih.gov/pubmed/24451403
http://dx.doi.org/10.3390/ph7010046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915194/
https://www.ncbi.nlm.nih.gov/pubmed/24451403
http://dx.doi.org/10.3390/ph7010046

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