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Ritonavir-Mediated Induction of Apoptosis in Pancreatic Cancer Occurs via the RB/E2F-1 and AKT Pathways
Recent observations suggest a lower incidence of malignancies in patients infected with HIV during treatment with Highly Active Anti-Retroviral Therapy (HAART) utilizing protease inhibitors. We investigated the effects of ritonavir, a FDA approved HIV protease inhibitor, on proliferation of pancreat...
Autores principales: | Batchu, Ramesh B., Gruzdyn, Oksana V., Bryant, Christopher S., Qazi, Aamer M., Kumar, Sanjeev, Chamala, Sreedhar, Kung, Shu T., Sanka, Ramana S., Puttagunta, Udaya S., Weaver, Donald W., Gruber, Scott A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915194/ https://www.ncbi.nlm.nih.gov/pubmed/24451403 http://dx.doi.org/10.3390/ph7010046 |
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