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DNA Methylation in Oocytes and Liver of Female Mice and Their Offspring: Effects of High-Fat-Diet–Induced Obesity

Background: Maternal obesity has adverse effects on oocyte quality, embryo development, and the health of the offspring. Objectives: To understand the underlying mechanisms responsible for the negative effects of maternal obesity, we investigated the DNA methylation status of several imprinted genes...

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Detalles Bibliográficos
Autores principales: Ge, Zhao-Jia, Luo, Shi-Ming, Lin, Fei, Liang, Qiu-Xia, Huang, Lin, Wei, Yan-Chang, Hou, Yi, Han, Zhi-Ming, Schatten, Heide, Sun, Qing-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915265/
https://www.ncbi.nlm.nih.gov/pubmed/24316659
http://dx.doi.org/10.1289/ehp.1307047