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Kynurenines in CNS disease: regulation by inflammatory cytokines

The kynurenine pathway (KP) metabolizes the essential amino acid tryptophan and generates a number of neuroactive metabolites collectively called the kynurenines. Segregated into at least two distinct branches, often termed the “neurotoxic” and “neuroprotective” arms of the KP, they are regulated by...

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Detalles Bibliográficos
Autores principales: Campbell, Brian M., Charych, Erik, Lee, Anna W., Möller, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915289/
https://www.ncbi.nlm.nih.gov/pubmed/24567701
http://dx.doi.org/10.3389/fnins.2014.00012