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Kynurenines in CNS disease: regulation by inflammatory cytokines
The kynurenine pathway (KP) metabolizes the essential amino acid tryptophan and generates a number of neuroactive metabolites collectively called the kynurenines. Segregated into at least two distinct branches, often termed the “neurotoxic” and “neuroprotective” arms of the KP, they are regulated by...
Autores principales: | Campbell, Brian M., Charych, Erik, Lee, Anna W., Möller, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915289/ https://www.ncbi.nlm.nih.gov/pubmed/24567701 http://dx.doi.org/10.3389/fnins.2014.00012 |
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