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Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation
The aggregation of amyloid-β peptides into protein fibres is one of the main neuropathological features of Alzheimer's disease (AD). While imaging of amyloid-β aggregate morphology in vitro is extremely important for understanding AD pathology and in the development of aggregation inhibitors, u...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915309/ https://www.ncbi.nlm.nih.gov/pubmed/24500006 http://dx.doi.org/10.1038/srep04004 |