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Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation

The aggregation of amyloid-β peptides into protein fibres is one of the main neuropathological features of Alzheimer's disease (AD). While imaging of amyloid-β aggregate morphology in vitro is extremely important for understanding AD pathology and in the development of aggregation inhibitors, u...

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Detalles Bibliográficos
Autores principales:	Tinker-Mill, Claire, Mayes, Jennifer, Allsop, David, Kolosov, Oleg V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915309/ https://www.ncbi.nlm.nih.gov/pubmed/24500006 http://dx.doi.org/10.1038/srep04004

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