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Damaged mitochondria and overproduction of ROS in Fanconi anemia cells
Fanconi anemia (FA) is a heterogeneous disease associated with a bone marrow failure, cancer predisposition and hypersensitivity to DNA crosslinking agents. To date, 15 different genes have been shown to cause FA, all of which have some role in repair of defective DNA interstrand crosslinks. On a bi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915560/ https://www.ncbi.nlm.nih.gov/pubmed/25002988 http://dx.doi.org/10.4161/rdis.24048 |