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Damaged mitochondria and overproduction of ROS in Fanconi anemia cells

Fanconi anemia (FA) is a heterogeneous disease associated with a bone marrow failure, cancer predisposition and hypersensitivity to DNA crosslinking agents. To date, 15 different genes have been shown to cause FA, all of which have some role in repair of defective DNA interstrand crosslinks. On a bi...

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Detalles Bibliográficos
Autor principal:	Lyakhovich, Alex
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Addendum
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915560/ https://www.ncbi.nlm.nih.gov/pubmed/25002988 http://dx.doi.org/10.4161/rdis.24048

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