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Unfolded protein response, treatment and CMT1B

CMT1B is the second most frequent autosomal dominant inherited neuropathy and is caused by assorted mutations of the myelin protein zero (MPZ) gene. MPZ mutations cause neuropathy gain of function mechanisms that are largely independent MPZs normal role of mediating myelin compaction. Whether there...

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Detalles Bibliográficos
Autores principales: Bai, Yunhong, Patzko, Agnes, Shy, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915562/
https://www.ncbi.nlm.nih.gov/pubmed/25002989
http://dx.doi.org/10.4161/rdis.24049