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Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism

Entamoeba histolytica is an extracellular tissue parasite causing colitis and occasional liver abscess in humans. E. histolytica-derived secretory products (SPs) contain large amounts of cysteine proteases (CPs), one of the important amoebic virulence factors. Although tissue-residing mast cells pla...

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Detalles Bibliográficos
Autores principales: Lee, Young Ah, Nam, Young Hee, Min, Arim, Kim, Kyeong Ah, Nozaki, Tomoyoshi, Saito-Nakano, Yumiko, Mirelman, David, Shin, Myeong Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915631/
https://www.ncbi.nlm.nih.gov/pubmed/24502918
http://dx.doi.org/10.1051/parasite/2014001