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hARACNe: improving the accuracy of regulatory model reverse engineering via higher-order data processing inequality tests
A key goal of systems biology is to elucidate molecular mechanisms associated with physiologic and pathologic phenotypes based on the systematic and genome-wide understanding of cell context-specific molecular interaction models. To this end, reverse engineering approaches have been used to systemat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915831/ https://www.ncbi.nlm.nih.gov/pubmed/24511376 http://dx.doi.org/10.1098/rsfs.2013.0011 |