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hARACNe: improving the accuracy of regulatory model reverse engineering via higher-order data processing inequality tests

A key goal of systems biology is to elucidate molecular mechanisms associated with physiologic and pathologic phenotypes based on the systematic and genome-wide understanding of cell context-specific molecular interaction models. To this end, reverse engineering approaches have been used to systemat...

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Detalles Bibliográficos
Autores principales: Jang, In Sock, Margolin, Adam, Califano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915831/
https://www.ncbi.nlm.nih.gov/pubmed/24511376
http://dx.doi.org/10.1098/rsfs.2013.0011