Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone

Proper activation of protein phosphatase 2A (PP2A) catalytic subunit is central for the complex PP2A regulation and is crucial for broad aspects of cellular function. The crystal structure of PP2A bound to PP2A phosphatase activator (PTPA) and ATPγS reveals that PTPA makes broad contacts with the st...

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Detalles Bibliográficos
Autores principales: Guo, Feng, Stanevich, Vitali, Wlodarchak, Nathan, Sengupta, Rituparna, Jiang, Li, Satyshur, Kenneth A, Xing, Yongna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915903/
https://www.ncbi.nlm.nih.gov/pubmed/24100351
http://dx.doi.org/10.1038/cr.2013.138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915903/
https://www.ncbi.nlm.nih.gov/pubmed/24100351
http://dx.doi.org/10.1038/cr.2013.138

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