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Overexpressing Sonic Hedgehog Peptide Restores Periosteal Bone Formation in a Murine Bone Allograft Transplantation Model

Although activation of hedgehog (Hh) signaling has been shown to induce osteogenic differentiation in vitro and bone formation in vivo, the underlying mechanisms and the potential use of Hh-activated mesenchymal progenitors in bone defect repair remain elusive. In this study, we demonstrated that im...

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Detalles Bibliográficos
Autores principales: Huang, Chunlan, Tang, Minghui, Yehling, Eric, Zhang, Xinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916037/
https://www.ncbi.nlm.nih.gov/pubmed/24089140
http://dx.doi.org/10.1038/mt.2013.222