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Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas

BACKGROUND: Interactions between cancer cells and surrounding cancer-associated fibroblasts (CAFs) play an important role in cancer progression. Invasive ductal carcinoma (IDC) of the pancreas is characterized by abundant fibrous connective tissue called desmoplasia. Podoplanin (PDPN) is a lymphatic...

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Detalles Bibliográficos
Autores principales: Shindo, Koji, Aishima, Shinichi, Ohuchida, Kenoki, Fujiwara, Kenji, Fujino, Minoru, Mizuuchi, Yusuke, Hattori, Masami, Mizumoto, Kazuhiro, Tanaka, Masao, Oda, Yoshinao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916072/
https://www.ncbi.nlm.nih.gov/pubmed/24354864
http://dx.doi.org/10.1186/1476-4598-12-168