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dsRNA-induced changes in gene expression profiles of primary nasal and bronchial epithelial cells from patients with asthma, rhinitis and controls

BACKGROUND: Rhinovirus infections are the most common cause of asthma exacerbations. The complex responses by airway epithelium to rhinovirus can be captured by gene expression profiling. We hypothesized that: a) upper and lower airway epithelium exhibit differential responses to double-stranded RNA...

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Detalles Bibliográficos
Autores principales: Wagener, Ariane H, Zwinderman, Aeilko H, Luiten, Silvia, Fokkens, Wytske J, Bel, Elisabeth H, Sterk, Peter J, van Drunen, Cornelis M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916078/
https://www.ncbi.nlm.nih.gov/pubmed/24475887
http://dx.doi.org/10.1186/1465-9921-15-9