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Bisphosphonates induce the osteogenic gene expression in co-cultured human endothelial and mesenchymal stem cells

Bisphosphonates (BPs) are known to affect bone homeostasis and also to have anti-angiogenic properties. Because of the intimate relationship between angiogenesis and osteogenesis, this study analysed the effects of Alendronate (AL) and Zoledronate (ZL) in the expression of endothelial and osteogenic...

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Detalles Bibliográficos
Autores principales: Ribeiro, Viviana, Garcia, Mónica, Oliveira, Raquel, Gomes, Pedro S, Colaço, Bruno, Fernandes, Maria Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916115/
https://www.ncbi.nlm.nih.gov/pubmed/24373581
http://dx.doi.org/10.1111/jcmm.12154