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ATF4 deficiency protects hepatocytes from oxidative stress via inhibiting CYP2E1 expression

Activating transcription factor (ATF) 4 is involved in the regulation of oxidative stress in fibroblasts and neurons. The role of ATF4 in hepatocytes, however, is unknown. The aim of this study was to investigate the role of ATF4 in hepatocytes in oxidative stress under a high-fat diet (HFD). Here,...

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Detalles Bibliográficos
Autores principales: Wang, Chunxia, Li, Houkai, Meng, Qingshu, Du, Ying, Xiao, Fei, Zhang, Qian, Yu, Junjie, Li, Kai, Chen, Shanghai, Huang, Zhiying, Liu, Bin, Guo, Feifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916120/
https://www.ncbi.nlm.nih.gov/pubmed/24373582
http://dx.doi.org/10.1111/jcmm.12166