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ATF4 deficiency protects hepatocytes from oxidative stress via inhibiting CYP2E1 expression
Activating transcription factor (ATF) 4 is involved in the regulation of oxidative stress in fibroblasts and neurons. The role of ATF4 in hepatocytes, however, is unknown. The aim of this study was to investigate the role of ATF4 in hepatocytes in oxidative stress under a high-fat diet (HFD). Here,...
Autores principales: | Wang, Chunxia, Li, Houkai, Meng, Qingshu, Du, Ying, Xiao, Fei, Zhang, Qian, Yu, Junjie, Li, Kai, Chen, Shanghai, Huang, Zhiying, Liu, Bin, Guo, Feifan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916120/ https://www.ncbi.nlm.nih.gov/pubmed/24373582 http://dx.doi.org/10.1111/jcmm.12166 |
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