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A Structural Biology Approach to Understand Human Lymphatic Filarial Infection

The presence of aspartic protease inhibitor in filarial parasite Brugia malayi (Bm-Aspin) makes it interesting to study because of the fact that the filarial parasite never encounters the host digestive system. Here, the aspartic protease inhibition kinetics of Bm-Aspin and its NMR structural charac...

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Detalles Bibliográficos
Autores principales: Nagampalli, Raghavendra Sashi Krishna, Gunasekaran, Krishnasamy, Narayanan, Rangarajan Badri, Peters, Angela, Bhaskaran, Rajagopalan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916234/
https://www.ncbi.nlm.nih.gov/pubmed/24516678
http://dx.doi.org/10.1371/journal.pntd.0002662