DAF-16/FoxO Directly Regulates an Atypical AMP-Activated Protein Kinase Gamma Isoform to Mediate the Effects of Insulin/IGF-1 Signaling on Aging in Caenorhabditis elegans

The DAF-16/FoxO transcription factor controls growth, metabolism and aging in Caenorhabditis elegans. The large number of genes that it regulates has been an obstacle to understanding its function. However, recent analysis of transcript and chromatin profiling implies that DAF-16 regulates relativel...

Descripción completa

Detalles Bibliográficos
Autores principales: Tullet, Jennifer M. A., Araiz, Caroline, Sanders, Matthew J., Au, Catherine, Benedetto, Alexandre, Papatheodorou, Irene, Clark, Emily, Schmeisser, Kathrin, Jones, Daniel, Schuster, Eugene F., Thornton, Janet M., Gems, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916255/
https://www.ncbi.nlm.nih.gov/pubmed/24516399
http://dx.doi.org/10.1371/journal.pgen.1004109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916255/
https://www.ncbi.nlm.nih.gov/pubmed/24516399
http://dx.doi.org/10.1371/journal.pgen.1004109

Ejemplares similares