Euchromatic Transposon Insertions Trigger Production of Novel Pi- and Endo-siRNAs at the Target Sites in the Drosophila Germline

The control of transposable element (TE) activity in germ cells provides genome integrity over generations. A distinct small RNA–mediated pathway utilizing Piwi-interacting RNAs (piRNAs) suppresses TE expression in gonads of metazoans. In the fly, primary piRNAs derive from so-called piRNA clusters,...

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Detalles Bibliográficos
Autores principales: Shpiz, Sergey, Ryazansky, Sergei, Olovnikov, Ivan, Abramov, Yuri, Kalmykova, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916259/
https://www.ncbi.nlm.nih.gov/pubmed/24516406
http://dx.doi.org/10.1371/journal.pgen.1004138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916259/
https://www.ncbi.nlm.nih.gov/pubmed/24516406
http://dx.doi.org/10.1371/journal.pgen.1004138

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