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Coherent Functional Modules Improve Transcription Factor Target Identification, Cooperativity Prediction, and Disease Association
Transcription factors (TFs) are fundamental controllers of cellular regulation that function in a complex and combinatorial manner. Accurate identification of a transcription factor's targets is essential to understanding the role that factors play in disease biology. However, due to a high fal...
Autores principales: | Karczewski, Konrad J., Snyder, Michael, Altman, Russ B., Tatonetti, Nicholas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916285/ https://www.ncbi.nlm.nih.gov/pubmed/24516403 http://dx.doi.org/10.1371/journal.pgen.1004122 |
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