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Evaluation in Mice of a Conjugate Vaccine for Cholera Made from Vibrio cholerae O1 (Ogawa) O-Specific Polysaccharide

BACKGROUND: Protective immunity against cholera is serogroup specific. Serogroup specificity in Vibrio cholerae is determined by the O-specific polysaccharide (OSP) of lipopolysaccharide (LPS). Generally, polysaccharides are poorly immunogenic, especially in young children. METHODOLOGY: Here we repo...

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Detalles Bibliográficos
Autores principales: Alam, Mohammad Murshid, Bufano, Megan Kelly, Xu, Peng, Kalsy, Anuj, Yu, Y., Freeman, Y. Wu, Sultana, Tania, Rashu, Md. Rasheduzzaman, Desai, Ishaan, Eckhoff, Grace, Leung, Daniel T., Charles, Richelle C., LaRocque, Regina C., Harris, Jason B., Clements, John D., Calderwood, Stephen B., Qadri, Firdausi, Vann, W. F., Kováč, Pavol, Ryan, Edward T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916310/
https://www.ncbi.nlm.nih.gov/pubmed/24516685
http://dx.doi.org/10.1371/journal.pntd.0002683