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Evaluation in Mice of a Conjugate Vaccine for Cholera Made from Vibrio cholerae O1 (Ogawa) O-Specific Polysaccharide
BACKGROUND: Protective immunity against cholera is serogroup specific. Serogroup specificity in Vibrio cholerae is determined by the O-specific polysaccharide (OSP) of lipopolysaccharide (LPS). Generally, polysaccharides are poorly immunogenic, especially in young children. METHODOLOGY: Here we repo...
Autores principales: | Alam, Mohammad Murshid, Bufano, Megan Kelly, Xu, Peng, Kalsy, Anuj, Yu, Y., Freeman, Y. Wu, Sultana, Tania, Rashu, Md. Rasheduzzaman, Desai, Ishaan, Eckhoff, Grace, Leung, Daniel T., Charles, Richelle C., LaRocque, Regina C., Harris, Jason B., Clements, John D., Calderwood, Stephen B., Qadri, Firdausi, Vann, W. F., Kováč, Pavol, Ryan, Edward T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916310/ https://www.ncbi.nlm.nih.gov/pubmed/24516685 http://dx.doi.org/10.1371/journal.pntd.0002683 |
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