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Slow Turnover of HIV-1 Receptors on Quiescent CD4(+) T Cells Causes Prolonged Surface Retention of gp120 Immune Complexes In Vivo

Peripheral blood CD4(+) T cells in HIV-1(+) patients are coated with Ig. However, the causes and consequences of the presence of Ig(+) CD4(+) T cells remain unknown. Previous studies have demonstrated the rapid turnover of viral receptors (VRs) on lymphoma and tumor cells. The present study investig...

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Detalles Bibliográficos
Autores principales: Suzuki, Yasuhiro, Gatanaga, Hiroyuki, Tachikawa, Natsuo, Oka, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916329/
https://www.ncbi.nlm.nih.gov/pubmed/24516533
http://dx.doi.org/10.1371/journal.pone.0086479