Inducible Deletion of CD28 Prior to Secondary Nippostrongylus brasiliensis Infection Impairs Worm Expulsion and Recall of Protective Memory CD4(+) T Cell Responses

IL-13 driven Th2 immunity is indispensable for host protection against infection with the gastrointestinal nematode Nippostronglus brasiliensis. Disruption of CD28 mediated costimulation impairs development of adequate Th2 immunity, showing an importance for CD28 during the initiation of an immune r...

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Detalles Bibliográficos
Autores principales: Ndlovu, Hlumani, Darby, Mathew, Froelich, Monika, Horsnell, William, Lühder, Fred, Hünig, Thomas, Brombacher, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916406/
https://www.ncbi.nlm.nih.gov/pubmed/24516382
http://dx.doi.org/10.1371/journal.ppat.1003906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916406/
https://www.ncbi.nlm.nih.gov/pubmed/24516382
http://dx.doi.org/10.1371/journal.ppat.1003906

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