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Enhanced antitumor activity of realgar mediated by milling it to nanosize

Realgar is a poorly water-soluble compound that exhibits poor bioavailability. To improve this, the authors reduced the particle size of realgar to nanoscale by high-energy ball milling and optimized the preparation process under which (realgar weight 40 g, milling time 9 hours, milling speed 38 Hz,...

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Detalles Bibliográficos
Autores principales: Tian, Ye, Wang, Xiaobo, Xi, Ronggang, Pan, Weisan, Jiang, Shuang, Li, Zhao, Zhao, Yu, Gao, Guanghui, Liu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916444/
https://www.ncbi.nlm.nih.gov/pubmed/24516332
http://dx.doi.org/10.2147/IJN.S56391