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Enhanced antitumor activity of realgar mediated by milling it to nanosize
Realgar is a poorly water-soluble compound that exhibits poor bioavailability. To improve this, the authors reduced the particle size of realgar to nanoscale by high-energy ball milling and optimized the preparation process under which (realgar weight 40 g, milling time 9 hours, milling speed 38 Hz,...
Autores principales: | Tian, Ye, Wang, Xiaobo, Xi, Ronggang, Pan, Weisan, Jiang, Shuang, Li, Zhao, Zhao, Yu, Gao, Guanghui, Liu, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916444/ https://www.ncbi.nlm.nih.gov/pubmed/24516332 http://dx.doi.org/10.2147/IJN.S56391 |
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