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Impaired activity-dependent neural circuit assembly and refinement in autism spectrum disorder genetic models
Early-use activity during circuit-specific critical periods refines brain circuitry by the coupled processes of eliminating inappropriate synapses and strengthening maintained synapses. We theorize these activity-dependent (A-D) developmental processes are specifically impaired in autism spectrum di...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916725/ https://www.ncbi.nlm.nih.gov/pubmed/24570656 http://dx.doi.org/10.3389/fncel.2014.00030 |