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Impaired activity-dependent neural circuit assembly and refinement in autism spectrum disorder genetic models

Early-use activity during circuit-specific critical periods refines brain circuitry by the coupled processes of eliminating inappropriate synapses and strengthening maintained synapses. We theorize these activity-dependent (A-D) developmental processes are specifically impaired in autism spectrum di...

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Detalles Bibliográficos
Autores principales:	Doll, Caleb A., Broadie, Kendal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916725/ https://www.ncbi.nlm.nih.gov/pubmed/24570656 http://dx.doi.org/10.3389/fncel.2014.00030

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