Antioxidant Supplementation Reduces Genomic Aberrations in Human Induced Pluripotent Stem Cells

Somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) using oncogenic transcription factors. However, this method leads to genetic aberrations in iPSCs via unknown mechanisms, which may limit their clinical use. Here, we demonstrate that the supplementation of growth media with...

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Detalles Bibliográficos
Autores principales: Ji, Junfeng, Sharma, Vivek, Qi, Suxia, Guarch, Meritxell Espino, Zhao, Ping, Luo, Zhiwei, Fan, Wenxia, Wang, Yu, Mbabaali, Faridah, Neculai, Dante, Esteban, Miguel Angel, McPherson, John D., Batada, Nizar N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916753/
https://www.ncbi.nlm.nih.gov/pubmed/24511469
http://dx.doi.org/10.1016/j.stemcr.2013.11.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916753/
https://www.ncbi.nlm.nih.gov/pubmed/24511469
http://dx.doi.org/10.1016/j.stemcr.2013.11.004

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