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A Panel of CpG Methylation Sites Distinguishes Human Embryonic Stem Cells and Induced Pluripotent Stem Cells

Whether human induced pluripotent stem cells (hiPSCs) are epigenetically identical to human embryonic stem cells (hESCs) has been debated in the stem cell field. In this study, we analyzed DNA methylation patterns in a large number of hiPSCs (n = 114) and hESCs (n = 155), and identified a panel of 8...

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Detalles Bibliográficos
Autores principales: Huang, Kevin, Shen, Yin, Xue, Zhigang, Bibikova, Marina, April, Craig, Liu, Zhenshan, Cheng, Linzhao, Nagy, Andras, Pellegrini, Matteo, Fan, Jian-Bing, Fan, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916755/
https://www.ncbi.nlm.nih.gov/pubmed/24511466
http://dx.doi.org/10.1016/j.stemcr.2013.11.003