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Simvastatin Promotes Adult Hippocampal Neurogenesis by Enhancing Wnt/β-Catenin Signaling

Statins improve recovery from traumatic brain injury and show promise in preventing Alzheimer disease. However, the mechanisms by which statins may be therapeutic for neurological conditions are not fully understood. In this study, we present the initial evidence that oral administration of simvasta...

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Detalles Bibliográficos
Autores principales: Robin, Nicholas C., Agoston, Zsuzsa, Biechele, Travis L., James, Richard G., Berndt, Jason D., Moon, Randall T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916759/
https://www.ncbi.nlm.nih.gov/pubmed/24511465
http://dx.doi.org/10.1016/j.stemcr.2013.11.002