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Screening of commercial cyclic peptide as inhibitor NS5 methyltransferase of Dengue virus through Molecular Docking and Molecular Dynamics Simulation

Dengue has become a major global health threat, especially in tropical and subtropical regions. The development of antiviral agent targeting viral replication is really needed at this time. NS5 methyltransferase presents as a novel antiviral target. This enzyme plays an important role in the methyla...

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Detalles Bibliográficos
Autores principales: Tambunan, Usman Sumo Friend, Zahroh, Hilyatuz, Utomo, Bimo Budi, Parikesit, Arli Aditya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916815/
https://www.ncbi.nlm.nih.gov/pubmed/24516322
http://dx.doi.org/10.6026/97320630010023