Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development

Innate-like, evolutionarily conserved MR1-restricted mucosa-associated invariant T (MAIT) cells represent a large antimicrobial T-cell subset in humans. Here, we investigate the development of these cells in second trimester human fetal tissues. MAIT cells are rare and immature in the fetal thymus,...

Descripción completa

Detalles Bibliográficos
Autores principales: Leeansyah, Edwin, Loh, Liyen, Nixon, Douglas F., Sandberg, Johan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916833/
https://www.ncbi.nlm.nih.gov/pubmed/24452018
http://dx.doi.org/10.1038/ncomms4143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916833/
https://www.ncbi.nlm.nih.gov/pubmed/24452018
http://dx.doi.org/10.1038/ncomms4143

Ejemplares similares