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Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development
Innate-like, evolutionarily conserved MR1-restricted mucosa-associated invariant T (MAIT) cells represent a large antimicrobial T-cell subset in humans. Here, we investigate the development of these cells in second trimester human fetal tissues. MAIT cells are rare and immature in the fetal thymus,...
Autores principales: | Leeansyah, Edwin, Loh, Liyen, Nixon, Douglas F., Sandberg, Johan K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916833/ https://www.ncbi.nlm.nih.gov/pubmed/24452018 http://dx.doi.org/10.1038/ncomms4143 |
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