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Actomyosin-dependent formation of the mechanosensitive talin–vinculin complex reinforces actin anchoring
The force generated by the actomyosin cytoskeleton controls focal adhesion dynamics during cell migration. This process is thought to involve the mechanical unfolding of talin to expose cryptic vinculin-binding sites. However, the ability of the actomyosin cytoskeleton to directly control the format...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916842/ https://www.ncbi.nlm.nih.gov/pubmed/24452080 http://dx.doi.org/10.1038/ncomms4095 |