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The Leishmania major BBSome subunit BBS1 is essential for parasite virulence in the mammalian host

Bardet–Biedl syndrome (BBS) is a human genetic disorder with a spectrum of symptoms caused by primary cilium dysfunction. The disease is caused by mutations in one of at least 17 identified genes, of which seven encode subunits of the BBSome, a protein complex required for specific trafficking event...

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Detalles Bibliográficos
Autores principales: Price, Helen P, Paape, Daniel, Hodgkinson, Michael R, Farrant, Katie, Doehl, Johannes, Stark, Meg, Smith, Deborah F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916885/
https://www.ncbi.nlm.nih.gov/pubmed/23998526
http://dx.doi.org/10.1111/mmi.12383