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RNAi Factors are Present and Active in Human Cell Nuclei
RNAi is widely appreciated as a powerful regulator of mRNA translation in the cytoplasm of mammalian cells. However, the presence and activity of RNAi factors in the mammalian nucleus has been the subject of considerable debate. Here we show that Argonaute-2 (Ago2) and RNAi factors Dicer, TRBP and T...
Autores principales: | Gagnon, Keith T., Li, Liande, Chu, Yongjun, Janowski, Bethany A., Corey, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916906/ https://www.ncbi.nlm.nih.gov/pubmed/24388755 http://dx.doi.org/10.1016/j.celrep.2013.12.013 |
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