GRIM-19 mutations fail to inhibit v-Src-induced oncogenesis

The non-receptor tyrosine kinase Src is a major player in multiple physiological responses including growth, survival and differentiation. Overexpression and/or oncogenic mutation in the Src gene have been documented in human tumors. The v-Src protein is an oncogenic mutant of Src, which promotes ce...

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Detalles Bibliográficos
Autores principales: Kalakonda, Sudhakar, Nallar, Shreeram C., Lindner, Daniel J., Sun, Peng, Lorenz, Robert R., Lamarre, Eric, Reddy, Sekhar P., Kalvakolanu, Dhananjaya V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916943/
https://www.ncbi.nlm.nih.gov/pubmed/23851499
http://dx.doi.org/10.1038/onc.2013.271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916943/
https://www.ncbi.nlm.nih.gov/pubmed/23851499
http://dx.doi.org/10.1038/onc.2013.271

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