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Nephrotoxicity of cefepime: A new cephalosporin antibiotic in rats

OBJECTIVES: To investigate the nephrotoxic effect and biochemical alterations induced by cefepime in rats. MATERIALS AND METHODS: Cefepime was administered intramuscularly at doses of 45, 90 and 180 mg/kg b.wt. once daily for 5 consecutive days. The serum and urine samples were used for quantitative...

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Detalles Bibliográficos
Autores principales: Elsayed, Mossad Gamaleddin Ahmed, Elkomy, Ashraf Abdelhakim Ahmed, Gaballah, Mahmoud Salem, Elbadawy, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917163/
https://www.ncbi.nlm.nih.gov/pubmed/24554908
http://dx.doi.org/10.4103/0976-500X.124419